The Hidden Metabolic Information of FFPE Tissue
For decades, Formalin-Fixed Paraffin-Embedded (FFPE) tissue has been the standard for preserving clinical samples. From cancer biopsies to organ tissue, this method is used across hospitals and research centers worldwide to store biological material for long-term use...
Using Metabolomics and Imaging to Track RLT Response
Radioligand therapy (RLT) represents a paradigm shift in precision oncology, delivering targeted radiation directly to cancer cells while minimizing damage to healthy tissue. Cell line-derived xenograft (CDX) models serve as essential platforms for RLT development,...
Mapping Signaling Drivers of Antibody Drug Conjugate Resistance
Antibody-drug conjugate (ADC) resistance represents one of the most formidable challenges in precision oncology, with clinical failures often attributed to our limited understanding of the dynamic molecular mechanisms underlying therapeutic escape. Panome Bio’s...