Imaging and Metabolomics in Radioligand Therapy
Connecting the Two Halves of the RLT Puzzle Understanding how radioligand therapy (RLT) works in cell line-derived xenograft (CDX) models requires connecting two complementary perspectives: Where the treatment goes, and What happens inside tumor cells once it gets...
Predicting RLT Resistance with Metabolomics and Imaging in Mice
Radioligand therapy (RLT) has emerged as a transformative precision oncology approach with remarkable initial response rates. However, treatment resistance remains a critical challenge that can limit long-term therapeutic success. Imaging technologies—including PET,...
Metabolomics in Alzheimer’s Disease
The Metabolic Frontier of Neuroscience: Lessons from Alzheimer’s Disease Alzheimer’s disease is a complex, devastating neurodegenerative disorder and the most common form of dementia, affecting millions globally. While decades of research have focused on the infamous...