Global Phosphoproteomics

Panome Bio’s global phosphoproteomics service provides researchers with an unbiased view and deeper understanding of phosphorylation events.

Many diseases begin at the protein-level and are associated with dysregulated protein phosphorylation signaling. Panome Bio’s LC-MS phosphoproteomics service offers a truly unbiased view of the proteome, enabling researchers to discover novel phosphorylation events and gain a deeper understanding of cellular signaling. The phosphoproteomics service entails a phosphopeptide enrichment to map phosphorylation events alongside a global proteomics assay for greater understanding. Panome Bio empowers researchers to better understand phosphorylation events with this comprehensive phosphoproteomics service, providing not just data, but actionable insights through rigorous statistical analysis and expert interpretation.

Advantages of our Global Phosphoproteomics Service:

• Can identify greater than 15,000 phosphopeptides across >7,000 unique proteins in a given sample.
• Our approach enables us to report signal intensities for all phosphorylation sites identified by using DIA mode MS. This approach scans the full range of masses and fragments and collects all ions, providing depth of coverage and reproducibility.
• Our analysis provides superior proteome coverage by utilizing the Orbitrap Astral MS.
• The unbiased, global view of the proteome and phosphorylation events provides immense discovery power.
• The global phosphoproteomics workflow is species agnostic, allowing for analysis of nearly any sample type.
• Our agnostic multi-omic pipeline can enhance the discovery potential of phosphoproteomics by integrating other ‘omic datasets, providing greater pathway coverage and hit confidence.