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Surface Proteomics for ADCs and CAR-T Design

Surface Proteomics for ADCs and CAR-T Design

Why Cell Therapy Target Selection Is So Difficult Antibody-drug conjugates (ADCs) and CAR-T therapies have reshaped modern oncology, but their success still depends on one deceptively simple question: are we targeting the right protein? In practice, answering this is...
Metabolomics in ADC & Immuno-Oncology

Metabolomics in ADC & Immuno-Oncology

Payload to Patient: Metabolomics in ADC and Immuno-Oncology In this episode of the ChatGJP series, Panome Bio CSO Dr. Gary J. Patti joins Chris Eden to explore real-world applications of metabolomics in antibody–drug conjugates (ADCs) and immuno-oncology. The...
Improving ADC Research via Surface Proteomics

Improving ADC Research via Surface Proteomics

Antibody-drug conjugates (ADCs) represent a paradigm shift in targeted cancer therapy, combining the specificity of monoclonal antibodies with the cytotoxic potency of small molecule drugs through sophisticated linker chemistry. Despite remarkable clinical successes...
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