This data report profiles metabolic alterations associated with ApoE deficiency using matched serum and liver samples from ApoE knockout and wild-type rats. The study identifies significantly altered metabolites, revealing systemic lipid remodeling and disruptions in sphingolipid metabolism. The report includes metabolite identification, differential abundance analysis, pathway enrichment, and biological interpretation to characterize metabolic changes associated with ApoE loss.
This data report has been reanalyzed using MassID™, incorporating enhanced metabolite identification capabilities. The updated analysis includes improved metabolite annotations, redesigned figures, and refined data visualization for greater clarity.
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