PRMT5 Metabolomics Panel for Patient Stratification
This poster presents a targeted, multiplexed LC-MS/MS metabolomics assay developed to support patient stratification and pharmacodynamic monitoring for MTA-cooperative PRMT5 inhibitors in oncology research. Leveraging Panome Bio’s specialized PRMT5 metabolomics panel, the assay enables sensitive and quantitative measurement of key metabolites associated with methylthioadenosine (MTA) biology and PRMT5 pathway activity.
This application demonstrates the value of targeted metabolomics in advancing precision oncology, offering a robust and scalable solution for integrating pharmacodynamic biomarkers into preclinical and clinical development of PRMT5 inhibitors.
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