Metabolomic Profiling of ApoE Deficiency Reveals Altered Lipid Metabolism This application note profiles metabolic alterations associated with ApoE deficiency using matched serum and liver samples from ApoE knockout and wild-type rats. Untargeted metabolomics identified significantly altered metabolites associated with systemic lipid remodeling and disruptions in sphingolipid metabolism.
This data report profiles metabolic alterations associated with ApoE deficiency using matched serum and liver samples from ApoE knockout and wild-type rats. The study identifies significantly altered metabolites, revealing systemic lipid remodeling and disruptions in sphingolipid metabolism. The report includes metabolite identification, differential abundance analysis, pathway enrichment, and biological interpretation to characterize metabolic changes associated […]
Advancing Animal Model Research with Multi-Omics Integration Discover how Panome Bio’s Next-Generation MetabolomicsTM and integrated multi-omics approaches enhance the translational value of animal model research. This application note demonstrates how comprehensive metabolic and molecular profiling enables deeper biological understanding, improving the accuracy and relevance of preclinical studies. Download to learn more about our data-driven insights […]