How Does Proteomics Complement Genomics in Understanding Disease? How does proteomics complement genomics in understanding disease? While genomics provides information about an individual’s genetic makeup and potential disease risk, proteomics offers a closer look at what is actually happening inside cells. In this episode of ChatGJP, Gary J. Patti, CSO of Panome Bio, explains how […]
What Can Metabolomics Reveal About Disease That Genomics Cannot? What can metabolomics reveal about disease that genomics might not be able to? While genomics provides critical information about an individual’s genetic makeup, it does not necessarily show what is happening within cells at the biochemical level. In this episode of ChatGJP, Gary J. Patti, CSO […]
Exposomics Reveals Differential Exposures And Chemical Subgroups ow can researchers identify which environmental chemicals differ between patient groups? How do they distinguish environmental exposures from naturally occurring metabolites? And how can machine learning uncover exposure patterns that researchers may not have anticipated? In this episode of ChatGJP, Ethan Stancliffe, Senior Director of R&D at Panome […]
Learn how untargeted metabolomics and lipidomics identify biomarkers that complement traditional methods for periodontitis diagnosis and oral health research.
How Genomics and Exposomics Will Transform Precision Medicine Genomics has transformed precision medicine by revealing an individual’s genetic blueprint—but genetics alone cannot explain why people with similar genomes often experience very different health outcomes. In this episode of ChatGJP, Panome Bio CEO Ed Weinstein explains how exposomics adds the missing layer by measuring the environmental […]
How Exposomics Can Improve Clinical Trials and Precision Medicine Why do promising drugs fail in Phase III clinical trials? Why do patients respond differently to the same therapy across countries? And if genetics only explains part of disease risk, what information is missing? In this episode of ChatGJP, Tom Cohen, President of Panome Bio, discusses […]
How are exposure patterns linked to biological pathways? Environmental chemical exposures can significantly influence drug metabolism, therapeutic response, and disease biology—but they are often overlooked in biomedical research and clinical development. In this episode of ChatGJP, Ethan Stancliffe, Senior Director of R&D, explains how environmental chemicals interact with cytochrome P450 enzymes, why chemical exposure burden […]
Learn how untargeted metabolomics and lipidomics identify biomarkers that complement traditional methods for periodontitis diagnosis and oral health research.
How Exposomics Is Measured: Sample Types, Sensitivity, and Workflows How are exposomics measurements performed, what sample types can be analyzed, and how sensitive are modern exposomics assays? In this episode of ChatGJP, Panome Bio VP of Operations Adam Richardson explains the technologies and workflows that enable comprehensive exposure profiling. The discussion explores how mass spectrometry […]
ChatGJP: Discovery vs Targeted Exposomics Explained Should you use discovery exposomics or targeted exposomics? In this episode of ChatGJP, Panome Bio CEO Ed Weinstein explains the strengths of each approach and how they work together to provide a comprehensive understanding of environmental chemical exposures. Discovery exposomics is an untargeted, hypothesis-generating strategy that screens broadly for […]