Advanced Microbiome Analysis with Next-Generation Metabolomics
Panome Bio offers a comprehensive microbiome function analysis that measures bile acids and short chain fatty acids (SCFAs), plus a global metabolomics screen for the broadest coverage and advanced understanding of the role of the microbiome in health and disease. Panome Bio also offers a multi-omics approach through integration of microbiome sequencing data with metabolomics. Integration of transcriptomics and metabolomics data can be used to identify gene-metabolite relationships, understand metabolic pathways, understand cellular response and mechanism of disease, and discover novel biomarkers and drug targets.
Global Metabolomics
- Important molecules measured include amino acids, sugars, nucleotides, nucleosides, and energy metabolites, among many others.
Bile Acid Assay
- Primary Bile Acids
- HumanCholic acid (CA); Chenodeoxycholic acid (CDCA); Glycine-CA; Glycine-CDCA; Taurine-CA
- Mousealpha/beta-Muricholic acid (a/b-MCA); omega-Muricholic acid (o-MCA); Gly-a/b-MCA; Taur-a/b-MCA
- Secondary Bile Acids
- Host-ConjugatedDeoxycholic acid (DCA); Lithocholic acid (LCA)
- FreeGlycine-DCA; Glycine-LCA
- Bile Acid Amidates
- BackboneGroup
- Chenodeoxycholic acidCysteine; Glutamic acid; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Tryptophan; Tyrosine
- Cholic acidAlanine; Arginine; Glutamic acid; Isoleucine; Leucine; Phenylalanine; Tryptophan; Tyrosine
- Deoxycholic acidGlutamic acid; Isoleucine; Leucine; Lysine; Methionine; Tryptophan; Tyrosine
- Hyocholic acidGlutamic acid
- Hyodeoxycholic acidGlutamic acid; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Tryptophan; Tyrosine
- Ursodeoxycholic acidGlutamic acid; Glutamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Tryptophan; Tyrosine
- Additional Bile Acids
- Hyocholic acid; Hyodeoxycholic acid; Ursodeoxycholic acid ; 3-Ketocholanic acid; Lithocholenic acid; 3b-Hydroxy-5-cholenoic acid; 8(14),(5β)-Cholenic acid-3α, 12α-diol; 5-β-Cholanic acid-3α-ol-6-one; Isolithocholic acid; Isodeoxycholic acid; 9(11), (5β)-Cholenic acid-3α-ol-12-one; 5α-Cholanic acid-3, 6-dione; 3,7-Dioxocholanic acid; 3,6-Dioxocholanic acid
Short Chain Fatty Acids (SCFAs)
- Short Chain Fatty Acids
- Butyrate, Isobutyrate
- 2-Hydroxybutryate (2-HB), 3-Hydroxybutryate (3-HB), 4-Hydroxybutryate (4-HB), 3-Hydroxyisobutyrate (3-HIB), 2-Methylbutyrate
- Caproate, Isocaproate, alpha-Ketoisocaproate (a-KIC)
- Valerate, Isovalerate, alpha-Ketoisovalerate (a-KIV), alpha-Ketomethylvalerate (a-KMV)
- Acetate, Acetone, Acetoacetate (AcAc)
- Propionate