Simultaneous Cell Surface Proteomics and Membrane Lipidomics
Cell Surface Multi-Omics is Panome Bio’s platform for simultaneously profiling the surface proteome and membrane lipidome from a single enriched membrane fraction. The cell surface is where cells communicate, respond to their environment, and interact with therapeutics, making it a critical but often incompletely characterized layer of biology. Cell Surface Multi-Omics combines LC-MS-based proteomics and membrane lipidomics with integrated computational analysis to reveal coordinated protein–lipid changes and uncover the mechanisms driving cell surface function.
Advantages to Cell Surface Multi-Omics
- Simultaneously measures cell surface proteins and membrane lipids from the same sample
- Integrates proteomic and lipidomic data to identify biologically relevant protein–lipid relationships
- Maps alterations to membrane biology frameworks including lipid rafts and phospholipid-dependent signaling
- Provides systems-level insight into cell surface remodeling and therapeutic mechanisms
Why Choose Panome Bio for Cell Surface Multi-Omics?
- Integrated platform purpose-built for simultaneous cell surface proteomics and membrane lipidomics
- High-confidence LC-MS workflows with advanced computational data integration
- Cross-layer analysis connecting protein expression with membrane lipid remodeling
- Supports applications including ADC and CAR-T research, immune evasion, ferroptosis, and therapeutic target discovery
- Seamlessly integrates with transcriptomics, metabolomics, and discovery proteomics for comprehensive multi-omic studies
Start Your Cell Surface Multi-Omics Study
Panome Bio’s integrated platform provides a complete picture of cell surface biology by combining high-confidence protein and lipid measurements with systems-level biological interpretation.
Contact our scientific team to design a Cell Surface Multi-Omics study tailored to your research needs.
Frequently Asked Questions
What is cell surface multi-omics?
Cell surface multi-omics is an integrated analysis that simultaneously measures cell surface proteins and membrane lipids from the same sample, revealing how proteins and lipids work together to drive cell surface function.
Why analyze cell surface proteins and lipids together instead of separately?
Measuring both layers from the same enriched membrane fraction avoids the variability of separate samples and reveals coordinated protein–lipid relationships, such as lipid raft organization and phospholipid-dependent signaling, that single-omics approaches can miss.
What research applications use cell surface multi-omics?
Common applications include ADC and CAR-T therapeutic research, immune evasion studies, ferroptosis research, and therapeutic target discovery.
Can cell surface multi-omics data be integrated with transcriptomics or discovery proteomics?
Yes. Cell Surface Multi-Omics is designed to integrate seamlessly with transcriptomics, metabolomics, and discovery proteomics for comprehensive multi-omic studies.