February 26, 2026
This publication from SynDevRx examines the dual anti-obesity and anti-tumor effects of Evexomostat (SDX-7320), a METAP2 inhibitor evaluated in diet-induced obese mouse and rat models. Using Next-Generation Metabolomics from Panome Bio, the study reveals distinct metabolic signatures that differentiate SDX-7320 from traditional weight-loss agents, aligning with its observed suppression of obesity-accelerated tumor growth. Integrated metabolic […]
December 5, 2025
Bioavailability studies in nutritional science traditionally focus on measuring the parent compound in circulation following dietary intake, typically through pharmacokinetic assessments that track maximum plasma concentration, time to peak levels, and area under the curve. While these measurements provide essential information about absorption efficiency, they reveal little about the metabolic fate of nutrients once they […]
November 25, 2025
Dietary intervention studies have historically relied on a limited panel of predefined endpoints: glucose and lipid profiles, inflammatory markers, anthropometric measurements, and questionnaire-based assessments. While these traditional biomarkers provide valuable information about specific physiological parameters, they represent only a narrow window into the complex biochemical changes that occur when dietary patterns are modified. This reductionist […]
June 24, 2025
This study from researchers at MaineHealth utilized Next-Generation Metabolomics to identify a cardioprotective signature in mouse blood plasma, and activated mitochondrial activity and energy production in liver and brown adipose tissue.. Read the article now to find out how Panome Bio is helping researchers better understand the underlying biological mechanisms of metabolic dysfunction.
February 18, 2025
Fructose consumption has skyrocketed in recent decades, but could this common sweetener be fueling cancer in unexpected ways? In this webinar, Ronald Fowle-Grider, PhD dives into new research uncovering how fructose indirectly enhances tumor growth—not by acting as a direct fuel, but by altering lipid metabolism in the liver.
January 23, 2025
Sex-Based Metabolomic Differences in Checkpoint Inhibitor Response This poster from our partners at TD2 (Translational Drug Development) highlights significant differences in tumor growth inhibition and treatment responses between obese and control diet-fed mice. Dive into the data, including flow cytometry, proteomics, and metabolomics analyses, to uncover the role of obesity in shaping the tumor microenvironment […]
December 13, 2023
Explore this white paper on Metabolomics and Metabolic Syndrome. Gain valuable insights into the intricate relationship between metabolism and disease, paving the way for innovative approaches to diagnostics and treatment.
September 29, 2023
Metabolomics can provide valuable information on the intricate connections between diet and metabolism, reshaping personalized nutrition and wellness strategies. With Panome Bio’s Next-Generation Metabolomics, gain deeper insights into the relationship between health and nutrition.
July 25, 2023
Explore insightful sample data analysis for metabolic flux data: Nutrient Contribution & Metabolic Flux in Metformin-treated HEK-293T Cells. Gain valuable metabolic insights with a data analysis report from Panome Bio.
