February 26, 2026
This publication from SynDevRx examines the dual anti-obesity and anti-tumor effects of Evexomostat (SDX-7320), a METAP2 inhibitor evaluated in diet-induced obese mouse and rat models. Using Next-Generation Metabolomics from Panome Bio, the study reveals distinct metabolic signatures that differentiate SDX-7320 from traditional weight-loss agents, aligning with its observed suppression of obesity-accelerated tumor growth. Integrated metabolic […]
February 26, 2026
Our partners at Indiana University leveraged Next-Generation Metabolomics to profile metabolic and lipidomic changes in gingival crevicular fluid from healthy individuals and patients with periodontitis. Using dual LC-MS platforms and deep-learning–assisted data curation, the study identified 256 differentially expressed metabolites, revealing elevated purine degradation products, increased ceramides, reduced oxy-fatty acids, and enrichment of known periodontitis […]
February 19, 2026
MassID is a computational tool that enables near-complete annotation of untargeted metabolomics datasets by assigning identification probabilities to detected features. Traditional workflows often leave many metabolites unannotated, limiting downstream biological interpretation. MassID overcomes these limitations, improving confidence in metabolite identification and supporting research in systems biology, biomarker discovery, and metabolomics-driven insights. MassID, Panome Bio’s identification […]
September 30, 2025
This study from researchers at the University of Arizona utilized Next-Generation Lipidomics from Panome Bio as part of a larger, multi-omic study to find that hypoxia promotes ferroptosis resistance in prostate cancer by altering lipid metabolism at the transcriptional level, by producing lipids that are less susceptible to peroxidation, and at the cellular level, by […]
June 24, 2025
This study from researchers at MaineHealth utilized Next-Generation Metabolomics to identify a cardioprotective signature in mouse blood plasma, and activated mitochondrial activity and energy production in liver and brown adipose tissue.. Read the article now to find out how Panome Bio is helping researchers better understand the underlying biological mechanisms of metabolic dysfunction.
December 17, 2024
This study from researchers at the University of Arizona utilized Next-Generation Metabolomics as part of a multi-omic study to understand prostate tumor metabolism. Download now to find out how Panome Bio is helping researchers better understand the underlying biological mechanisms of cancer.
