Bioprocessing - Panome Bio

Optimize Bioprocessing Parameters with Next-Generation Metabolomics™, Lipidomics and Proteomics

A bioprocess is a biological or biochemical technique used to produce a desired compound or product via living cells, organisms or their components. Understanding the mechanics of the metabolome and proteome can help pinpoint obstacles in cell growth and metabolism, leading to more efficient biological processes. With Panome Bio, it is possible to identify biomarkers unique to various culture methods, which could facilitate targeted optimization of growth media and many other variables of a bioprocess to significantly improve outcomes.

Optimize Bioprocessing Parameters with Next-Generation Metabolomics™, Lipidomics and Proteomics

Cell Media Analysis with Panome Bio

With Panome Bio’s multi-omic suite of capabilities, make new insights into the microenvironmental changes of your cell culture system. Gain information from your system on:

Nutrient Utilization
Nutrient Utilization
Comparing spent media at different timepoints can provide information on how nutrients are consumed during a cell culture process.
Metabolic Waste Product
Metabolic Waste Product
Spent media analysis captures information on metabolic waste products produced by cells in the bioreactor.
Metabolic Pathways
Metabolic Pathways
Identify lipids associated with specific pathways, biological functions or disease processes.

Improve Cultured Meat Characteristics with Panome Bio

Cultured meats, also known as cell-based meats or lab-grown meats, are made by culturing animal cells in a bioreactor and then using them to grow muscle tissue, which can then be harvested and processed into meat products. Metabolomics is able to analyze animal and plant metabolites, including both hydrophilic and hydrophobic compounds that are low in molecular weight. These molecules include important flavor, nutrient, and functionality-associated compounds that characterize the sensory and nutritional properties of food.

Improve Cultured Meat Characteristics with Panome Bio

By leveraging Panome Bio’s data for your cultured meats,
you can make informed adjustments on several variables:

Cell Source
Cell
Source
The choice of cell source can impact growth characteristics as well as the taste, texture and nutritional content of the final product.
Culture Medium
Culture
Medium
The composition of the culture medium can impact the growth rate as well as the quality of the cells and nutritional content of the final product.
Scaffold Material
Scaffold
Material
The choice of the scaffold material and scaffold design can impact the texture and structure of the final product.

With data from Panome Bio on your bioprocessing system,
you can make informed adjustments on several variables:

Cell Lines
Cell
Lines
A productive cell line must give consistent quality, productivity and growth characteristics while in the bioreactor.
Cell Media
Cell
Media
The composition of the culture medium can impact the growth rate as well as the quality of the cells and the nutritional content of the final product.
Supplementation Strategies
Supplementation
Strategies
Supplementation strategies are an integral part of fed-batch processes. Inadequate and over-supplementation can lead to undesirable results.
Bioreactor Conditions
Bioreactor
Conditions
The temperature, pH, oxygen levels and more will impact growth rate and quality of cells as well as the efficiency in which the cells expand.
Post-processing
Post-processing
Efficient post-processing methods must produce consistent, quality products and are directly related to the performance of a cell culture process.

Visit our resources section for more information on Panome Bio’s applications in bioprocessing!

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