- Metabolic flux analysis service providing real-time insight into pathway activity by tracking nutrient flow using stable isotope tracers.
- Stable isotope–based LC-MS workflows combined with advanced computation to isolate tracer-derived metabolites and accurately characterize isotopologue distributions.
- Next-Generation metabolic flux platform supporting drug mechanism studies, cancer metabolism research, metabolic disease investigation, host–microbiome interactions, and systems biology.
Metabolic flux analysis tracks how metabolites move through pathways, revealing critical insights into disease mechanisms and treatment development.
Metabolic flux analysis tracks how metabolites move through pathways, revealing critical insights into disease mechanisms and drug development. Using stable isotope labeling experiments, we uncover how fluxes—affected by transcriptional, translational, and post-translational changes—are disrupted in disease states. Our experts will guide you in choosing the ideal stable isotope precursor and designing optimal labeling conditions to maximize your results. Our flux experiments can cover:
- Pentose phosphate pathway
- Tricarboxylic Acid Cycle & Reductive Carboxylation
- Glycolysis
- Bioprocessing
Advantages of our Metabolic Flux Offering
- Metabolic flux information helps researchers understand how compounds are are transformed through pathways. This reveals how systems respond to changes in their environment, treatment, or genetic modifications.
- Helps identify rate-limiting steps in metabolic networks, offering insights for potential therapeutic targets or metabolic engineering.
- Integration with Multi-Omics Data: Complements genomic, transcriptomic, and proteomic data, enabling a more comprehensive understanding of the cellular metabolic state.
- Metabolic flux experiments are not only useful in disease pathogenesis and drug target discovery, it is a crucial concept in bioprocessing. Understanding metabolic flux can significantly impact bioprocessing by enhancing product yield and optimizing substrate utilization.
Nutrient Contribution and Metabolic Flux Analysis of Metformin treated HEK-293T Cells
See how metabolic flux was used to investigate nutrient contribution in cell lines.
Let’s get started!
Discover the unparalleled advantages of Panome Bio’s advanced metabolomics technology. Your research project is unique and we can provide a custom experimental design to meet your goals. Whether you are investigating a specific disease model, elucidating biomarkers for diagnostics, or evaluating therapeutic targets, Panome Bio will work with you to design a tailored approach to best suit your research goals.
Ready to elevate your research? Connect with us today and transform your research with metabolomics.