Imaging and Metabolomics in Radioligand Therapy
Connecting the Two Halves of the RLT Puzzle Understanding how radioligand therapy (RLT) works in cell line-derived xenograft (CDX) models requires connecting two complementary perspectives: Where the treatment goes, and What happens inside tumor cells once it gets...
Building Research Credibility with CLIA
How Quality Infrastructure Impacts Scientific Impact The scientific landscape has shifted dramatically as reproducibility concerns have fundamentally changed how reviewers evaluate manuscripts, how funding agencies assess proposals, and how collaborators choose...
Predicting and Overcoming RLT Resistance: How Metabolomics Enhances Imaging to Reveal Early Resistance Signatures in Mouse Models
Radioligand therapy (RLT) has emerged as a transformative precision oncology approach with remarkable initial response rates. However, treatment resistance remains a critical challenge that can limit long-term therapeutic success. Imaging technologies—including PET,...
The Metabolic Frontier of Neuroscience: Lessons from Alzheimer’s Disease
Alzheimer’s disease is a complex, devastating neurodegenerative disorder and the most common form of dementia, affecting millions globally. While decades of research have focused on the infamous amyloid plaques and tau tangles, a powerful new focus is emerging:...