True Global Metabolomics — An Unbiased View of Metabolism for Discovery
At Panome Bio, we utilize state-of-the-art liquid chromatography-mass spectrometry assays and data processing to give you the highest quality and most interpretable metabolomics and lipidomics data. Rather than just matching against predefined metabolite libraries, our untargeted metabolomics analysis scans the raw data for all metabolite signals present and matches those signals with confidence against comprehensive small molecule databases to provide an unbiased and global view of metabolism.
Next-Generation Metabolomics
Through a global metabolomics analysis and robust computational methods, Panome Bio provides an unbiased and comprehensive view of metabolism. We then use next-generation methods to decrease the complexity of datasets while delivering the biologically-relevant data. Our methods allow more impactful experimental designs than previously possible, including multi-omic integration, longitudinal analysis, dose-response studies, large cohorts, and more.
- Lipid Metabolism
- Amino Acid Metabolism
- Carbohydrate Metabolism
- Fatty Acid Metabolism
- Aging Metabolomics
- Cardiovascular Metabolomics
- Cancer Metabolism
- Metabolomics in Diabetes
Now Featuring — Dried Blood Spot Analysis
Dried Blood Spot (DBS) sampling is a minimally invasive, low-volume, and highly stable method ideal for a wide range of applications and offers significant logistical advantages including long-term room temperature stability and simple sample collection. Next-Generation Metabolomics technology has been proven to provide broad metabolite coverage with high accuracy when analyzing dried blood spot samples.
Frequently Asked Questions
What is untargeted (global) metabolomics?
Untargeted metabolomics scans raw LC-MS data for all detectable metabolite signals and matches them against comprehensive small molecule databases, rather than only measuring a predefined list of metabolites.
What is dried blood spot (DBS) metabolomics analysis?
DBS analysis is a minimally invasive, low-volume sampling method that offers long-term room-temperature stability and simple collection. Next-Generation Metabolomics has been validated to provide broad, accurate metabolite coverage from dried blood spot samples.
What areas of metabolism can Next-Generation Metabolomics assess?
The platform covers lipid, amino acid, carbohydrate, and fatty acid metabolism, and supports applications such as aging, cardiovascular, cancer, and diabetes metabolomics research.
How does Next-Generation Metabolomics differ from targeted metabolomics?
Next-Generation Metabolomics is untargeted, providing a comprehensive, unbiased view of all detectable metabolites, while targeted metabolomics quantifies a predefined, validated list of known metabolites.